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Cannabinoids

Cannabis plants contain varying profiles of effects depending on the strain – an important component being cannabinoids. The two best-known are THC and CBD. Learn more now about their diverse therapeutic effects

Cannabinoids – the main active ingredients in cannabis

Cannabinoids are chemical compounds. They activate the cannabinoid receptors in our bodies. Phytocannabinoids are the plant-derived forms of these chemical compounds: They are found in the highest concentrations in female cannabis flowers – more precisely, in the resin glands on the flower's surface. 

Today, more than 113 different cannabinoids are known. New ones are still being discovered. Some researchers now speak of 144 or more. Each cannabinoid has a unique effect on the endocannabinoid system (ECS), that is, the cannabinoid receptors in the body.

MEDCAN believes that all components of the cannabis plant – cannabinoids, terpenes, and other chemical compounds – work together to achieve the best therapeutic effect. This so-called entourage effect is confirmed by research and many patients worldwide. 

MEDCAN recommends using full-spectrum cannabis products or cannabis flowers. Do not use products containing isolated cannabinoids. Instead, focus on choosing the right cannabis strain to achieve the desired effect.

8 cannabinoids with medical potential

THC

Boiling point: 157 °C

Δ-9-Tetrahydrocannabinol (THC) is a cannabinoid known for its psychoactive effects. THC is illegal in Switzerland and is listed as a narcotic. One of the most important discoveries made through THC is the existence of the endocannabinoid system in the bodies of vertebrates and humans. Research suggests that THC interacts with parts of the brain that are otherwise controlled by the endogenous cannabinoid neurotransmitter anandamide

THCA

Boiling point: 105 °C

Tetrahydrocannabinolic acid (THCA) is the main component of fresh cannabis and, like other acid cannabinoids, is not psychoactive (the "A" stands for acid). THCA converts to D9-THC when it is burned, vaporized, or heated at a specific temperature for a certain period of time (decarboxylation).

Research into THCA is progressing steadily. It is still too early to make definitive statements about the therapeutic effects of this compound. However, preliminary studies point to medical benefits. THCA is potent anti-inflammatory, appetite-stimulating, anti-tumor, combats insomnia, and has anticonvulsant properties.

THCV

Boiling point: unknown

Tetrahydrocannabivarin (THCV) is found in high concentrations in cannabis strains native to Central Africa, such as certain phenotypes from Malawi. It is currently being researched as a treatment option for metabolic disorders, including diabetes, and as a potential appetite suppressant.

CBD

Boiling point: 180 °C

Cannabidiol (CBD) is non-psychoactive and, because it has only moderate side effects, is ideal for medical use in children and the elderly. CBD has anti-inflammatory properties, reduces pain, and shows good results in the treatment of tumors. It is beneficial for stress-related disorders and sleep problems. CBD is also used to mitigate the psychoactive effects of THC. Cannabis flowers and CBD products with less than 1% THC and a high CBD content are legally available in Switzerland and can be purchased in shops and online.

CBDA

Ideal decarbonization temperature: 120+ °C

CBD carboxylic acid (CBDA) is the main component of cannabis plants bred for increased CBD content. CBDA and THCA contain most of the anti-inflammatory properties that cannabis has to offer. CBDA has been shown to have both anti-inflammatory and anti-tumor effects.

CBN

Boiling point: 185 °C

Cannabinol (CBN) is an oxidation product of THC. It normally forms when THC is exposed to oxygen and heat. A high CBN level in cannabis suggests that it is old or has been exposed to excessive heat. CBN potentiates the effects of THC and is responsible for the so-called "couch-lock" effect—the feeling of extreme heaviness in the body. CBN has very mild psychoactive effects but is more sedating than other known cannabinoids. This explains its great potential for sleep therapy.

CBG

Boiling point: not available

Cannabigerol (CBG) is non-psychoactive and has been shown to stimulate the growth of new brain cells, even in older people. CBG also stimulates bone growth, has antibacterial and antitumor properties, and can help with insomnia. It can alter the overall effects of cannabis.

CBC

Boiling point: 220 °C

Cannabichromene (CBC) is also non-psychoactive and has proven to be about ten times more effective than CBD in treating anxiety and stress. It can also be used to treat inflammation and relieve pain. CBC is also antiviral and antitumor. Furthermore, it has been shown to stimulate bone tissue growth.